Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 163
interventional 122
Observational 35
Registry 6

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 39
Device 23
Procedure 19
Other 10
Drug|placebo 8
Behavioral 4
Drug|Other 4
Biological 3
Biological|placebo 2
Device|Drug 2
Device|Other 2
Diagnostic Test 2
Dietary Supplement|placebo 2
Other|placebo 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 22
NA 16
France 15
India 6
Thailand 6
China 4
Greece 4
Spain 4
Italy 3
Sweden 3
Austria 2
Brazil 2
Canada 2
Israel 2
Mexico 2
Russian Federation 2
Argentina|Brazil|Bulgaria|China|Czechia|France|Hungary|India|Italy|Japan|Korea, Republic of|Latvia|Mexico|Peru|Philippines|Poland|Romania|Russian Federation|Slovenia|South Africa|Spain|Taiwan|Turkey|Ukraine|United Kingdom|Vietnam 1
Australia 1
Australia|Canada 1
Belgium 1
Belgium|France|Guadeloupe|Réunion 1
Colombia 1
Germany 1
Greece|Spain 1
Hong Kong|Indonesia|Malaysia|Singapore|Vietnam 1
Japan 1
Nepal 1
Nepal|Singapore|Thailand 1
Poland 1
Romania 1
Slovenia 1
Switzerland 1
Tunisia 1
Turkey 1
Ukraine|United States|Argentina|Canada|Chile|Croatia|France|India|Russian Federation 1
United Kingdom 1
United States|Belarus|Belgium|Brazil|Estonia|France|Georgia|India|Israel|Latvia|Mexico|Russian Federation|Serbia|South Africa|Turkey|Ukraine 1
United States|Belgium|Canada|Czechia|Estonia|France|Georgia|Germany|Hungary|Israel|Japan|Latvia|Philippines|Puerto Rico|Russian Federation|Serbia|Spain|Taiwan|Ukraine 1
United States|Brazil|Croatia|France|Germany|Greece|Guatemala|Israel|Italy|Japan|Korea, Republic of|Spain|Taiwan|Thailand|Turkey|United Kingdom 1
United States|Canada 1
United States|Canada|Saudi Arabia 1
United States|Puerto Rico 1
Vietnam 1

Sites per Study

Site_count Study_Count
1 88
2 7
3 4
5 4
6 1
9 2
10 2
12 1
14 1
16 2
19 1
21 1
25 1
37 1
40 1
44 1
85 1
100 1
119 1
125 1

Phase

Phase Study_Count
N/A 61
Phase 3 20
Phase 4 19
Phase 2 13
Early Phase 1 3
Phase 1 2
Phase 1/Phase 2 2
Phase 2/Phase 3 2

Number of Arms

Number_of_Arms Count_of_Studies
1 15
2 79
3 10
4 5
5 1
NA 12

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 41.0 10.0000 12.0 15.00 16 20 34.0000 8.0000
1st Qu. 47.0 64.5000 45.5 20.25 40 25 138.5000 35.0000
Median 53.0 115.0000 79.0 25.50 146 30 240.0000 200.0000
Mean 82.0 282.4667 79.0 25.50 175 30 920.2105 317.5263
3rd Qu. 102.5 211.5000 112.5 30.75 192 35 613.0000 290.0000
Max. 152.0 3342.0000 146.0 36.00 547 40 10000.0000 2650.0000

Trial Group Type

group_type Group_Count
Experimental 113
Active Comparator 65
Placebo Comparator 22
No Intervention 18
NA 12
Other 8
Sham Comparator 2

Intervention Model

intervention_model Study_Count
Parallel Assignment 93
Single Group Assignment 19
Crossover Assignment 6
Factorial Assignment 4

Primary Purpose

primary_purpose Study_Count
Prevention 54
Treatment 49
Diagnostic 8
Supportive Care 4
NA 3
Health Services Research 2
Educational/Counseling/Training 1
Other 1

Observational Studies

Studies by Country

Country Study_Count
United States 7
NA 6
France 4
Hungary 2
United Kingdom 2
United States|Canada 2
Brazil 1
China 1
France|Italy 1
Germany 1
Greece 1
Italy 1
Italy|Romania|United Kingdom 1
Netherlands 1
Poland 1
Spain 1
Switzerland 1
Taiwan 1

Sites per Study

Site_count Study_Count
1 28
2 2
3 1
4 1
11 1
15 1
23 1

Enrollment Metrics

Measure Observational
Min 9.0000
1st Qu 49.0000
Median 100.0000
Mean 518.7143
3rd Qu 305.0000
Max 7530.0000

Observation Model

observational_model Study_Count
Cohort 21
Case-Control 3
Case-Only 3
Case Control 3
Other 2
Defined Population, Natural History 1
Ecologic or Community 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 27
Retrospective 4
Other 2
Cross-Sectional 1
Longitudinal, Prospective 1

Registries

Studies by Country

Country Study_Count
Turkey 2
France 1
Saudi Arabia 1
Switzerland 1
Tunisia 1

Sites per Study

Site_count Study_Count
1 6

Enrollment Metrics

Measure Registries
Min 30.0
1st Qu 42.5
Median 100.0
Mean 385.0
3rd Qu 180.0
Max 1850.0

Registry Model

observational_model Study_Count
Cohort 3
Case-Only 2
Case-Control 1

Time Perspective

time_perspective Study_Count
Prospective 5
Other 1

Follow-up

target_duration Study_Count
2 Weeks 1
2 Years 1
28 Days 1
5 Days 1
6 Months 1
7 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03401463 Assesment of the Endotracheal Tube Cuff Pressure Values in ICU Pateints Before and After Training Seminar https://ClinicalTrials.gov/show/NCT03401463 Completed Jagiellonian University 2018-06-30
NCT03382548 Defining Antibiotic Treatment Duration for Ventilator - Associated Lung Infection https://ClinicalTrials.gov/show/NCT03382548 Recruiting University of Oxford 2021-06-30
NCT03149640 Study Comparing Inhaled Amikacin Versus Placebo to Prevent Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT03149640 Recruiting University Hospital, Tours 2020-06-30
NCT03101202 To Compare Endotracheal Tube (ET) With Subglottic Suction Drainage and Standard ET in the Incidence of VAP https://ClinicalTrials.gov/show/NCT03101202 Completed All India Institute of Medical Sciences, New Delhi 2017-07-31
NCT03074552 Probiotic Prophylaxis for Microbiome Modulation and VAP or Infections Prevention in Multitrauma Patients https://ClinicalTrials.gov/show/NCT03074552 Recruiting Aristotle University Of Thessaloniki 2020-03-15
NCT03032380 Clinical Study of S-649266 for the Treatment of Nosocomial Pneumonia Caused by Gram-negative Pathogens https://ClinicalTrials.gov/show/NCT03032380 Completed Shionogi Inc. 2019-02-26
NCT02966392 Continuous Endotracheal Cuff Pressure Control to Prevent Ventilator Associated Respiratory Infections https://ClinicalTrials.gov/show/NCT02966392 Completed Oxford University Clinical Research Unit, Vietnam 2019-03-07
NCT02950519 Endotracheal Tube Cuff Pressures in Ventilated Patients https://ClinicalTrials.gov/show/NCT02950519 Completed Barnes-Jewish Hospital 2017-11-30
NCT02838160 Effectiveness of Different Educational Strategies on the KAP, Psychological and Clinical Outcomes https://ClinicalTrials.gov/show/NCT02838160 Completed Baqiyatallah Medical Sciences University 2015-06-30
NCT02837835 Lung Concentrations of Ceftazidime in Patients With Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT02837835 Completed CHU de Reims 2008-02-29
NCT02756351 A Efficacy and Safety Study of Nasal Prongs With Proprietary Surface Coating Aiming to Reduce Bacterial Colonization https://ClinicalTrials.gov/show/NCT02756351 Completed CytaCoat AB 2016-06-30
NCT02753608 Early Detection of Ventilator-associated Pneumonia (VAP) https://ClinicalTrials.gov/show/NCT02753608 Completed Jena University Hospital 2017-12-31
NCT02714595 Study of S-649266 or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens https://ClinicalTrials.gov/show/NCT02714595 Completed Shionogi Inc. 2019-04-01
NCT02704923 Atropine for Preventing Ventilator-Associated Pneumonia https://ClinicalTrials.gov/show/NCT02704923 Completed Universidade de Passo Fundo 2015-12-31
NCT02683603 Effect of Aerosolised Colistin in Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT02683603 Completed Tunis University 2015-04-30
NCT02652247 Serial, Non-invasive Analysis of Exhaled Breath Condensate in Ventilated Trauma Patients https://ClinicalTrials.gov/show/NCT02652247 Recruiting Vanderbilt University Medical Center 2020-06-30
NCT02615041 The Pharmacodynamics of Meropenem in Patient With Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT02615041 Completed Prince of Songkla University 2005-01-31
NCT02574130 Effect of Additional Nebulized Amikacin in Ventilator-Associated Pneumonia Caused by Gram Negative Bacteria https://ClinicalTrials.gov/show/NCT02574130 Completed Thammasat University 2018-04-30
NCT02542553 Bilateral Bronchoalveolar Lavage in Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT02542553 Completed Catholic University of the Sacred Heart 2014-07-31
NCT02515617 Medico-economic Study of the Subglottic Secretions Drainage in Prevention of Ventilator-associated Pneumonia (DEMETER) https://ClinicalTrials.gov/show/NCT02515617 Completed Centre Hospitalier Departemental Vendee 2018-11-22
NCT02515448 A Pharmacokinetic-pharmacodynamic Dose Comparison Study of 8 mg/kg of Inhaled or Parenteral Gentamicin in 12 Mechanically Ventilated Critically Ill Patients Treated for Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT02515448 Completed Poitiers University Hospital 2016-11-30
NCT02514655 Simple Mechanical Device to Control Pressure in the Balloon of the Endotracheal Tube to Prevent Ventilator-acquired Pneumonia https://ClinicalTrials.gov/show/NCT02514655 Recruiting Assistance Publique - Hôpitaux de Paris 2020-02-15
NCT02462590 Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial https://ClinicalTrials.gov/show/NCT02462590 Recruiting McMaster University 2020-12-31
NCT02389036 Selective Decontamination of the Digestive Tract in Intensive Care Unit Patients https://ClinicalTrials.gov/show/NCT02389036 Recruiting The George Institute 2021-12-31
NCT02288390 Oral Care as a Preventive Measure of VAP; Miswak Versus Chlorhexidine and Toothbrush. https://ClinicalTrials.gov/show/NCT02288390 Completed University of Alexandria 2008-05-31
NCT02284438 Biofilm Formation on Different Endotracheal Tube Materials https://ClinicalTrials.gov/show/NCT02284438 Completed Region Skane 2017-11-30
NCT02223988 Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage https://ClinicalTrials.gov/show/NCT02223988 Completed University of Turin, Italy 2016-06-30
NCT02186951 Antibiotherapy During Therapeutic Hypothermia to Prevent Infectious Complications https://ClinicalTrials.gov/show/NCT02186951 Completed University Hospital, Limoges 2016-10-27
NCT02120001 Efficacy Study on Silver-coated ETT Cleaned With a Novel Device https://ClinicalTrials.gov/show/NCT02120001 Completed Massachusetts General Hospital 2015-08-31
NCT02116699 Oropharyngeal Administration of Mother’s Colostrum for Premature Infants https://ClinicalTrials.gov/show/NCT02116699 Recruiting NorthShore University HealthSystem 2019-11-30
NCT02096328 Pharmacokinetics, Safety and Efficacy of POL7080 in Patients With Ventilator Associated Pseudomonas Aeruginosa Pneumonia https://ClinicalTrials.gov/show/NCT02096328 Completed Polyphor Ltd. 2015-12-31
NCT02077920 Methods of Chlorhexidine Cleansing to Prevent Ventilator-Associated Pneumonia (VAP) https://ClinicalTrials.gov/show/NCT02077920 Completed General Hospital of Shenyang Military Region 2019-06-30
NCT02070757 Safety and Efficacy Study of Ceftolozane/Tazobactam to Treat Ventilated Nosocomial Pneumonia (MK-7625A-008) https://ClinicalTrials.gov/show/NCT02070757 Completed Cubist Pharmaceuticals LLC 2018-05-15
NCT02060045 Prevention Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT02060045 Completed Hospital General Universitario Gregorio Marañon 2012-06-30
NCT01314742 Study of Biotene OralBalance Gel for Oral Care in Critically-Ill Mechanically Ventilated Neonates https://ClinicalTrials.gov/show/NCT01314742 Completed Wake Forest University Health Sciences 2012-01-31
NCT04269525 Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumonia https://ClinicalTrials.gov/show/NCT04269525 Recruiting Zhongnan Hospital 2020-12-01
NCT01972425 Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship https://ClinicalTrials.gov/show/NCT01972425 Completed Newcastle-upon-Tyne Hospitals NHS Trust 2016-09-30
NCT01948635 Impact of Tracheal Cuff Shape on Microaspiration in Intensive Care Units https://ClinicalTrials.gov/show/NCT01948635 Completed University Hospital, Lille 2015-08-31
NCT01935388 Common Canister Protocol for Inhaler Administration in Mechanically Ventilated Patients https://ClinicalTrials.gov/show/NCT01935388 Completed Barnes-Jewish Hospital 2016-02-29
NCT01808092 A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia https://ClinicalTrials.gov/show/NCT01808092 Completed Pfizer 2016-01-31
NCT01807884 Comparison of Two Strategies of Oropharyngeal and Tracheal Suctioning in Mechanically Ventilated Patients https://ClinicalTrials.gov/show/NCT01807884 Completed University Hospital, Bordeaux 2016-03-04
NCT01782755 Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial https://ClinicalTrials.gov/show/NCT01782755 Completed McMaster University 2014-08-31
NCT01765530 Efficacy Study of a Novel Device to Clean the Endotracheal Tube https://ClinicalTrials.gov/show/NCT01765530 Completed Massachusetts General Hospital 2013-12-31
NCT01744483 Endotracheal Tubes for Prevention of Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT01744483 Completed University of Washington 2015-10-31
NCT01657396 Implementation and Evaluation of Revised Protocols for Oral Hygiene for Mechanically Ventilated Patients https://ClinicalTrials.gov/show/NCT01657396 Completed University of Calgary 2012-10-31
NCT01640925 Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit https://ClinicalTrials.gov/show/NCT01640925 Completed The Methodist Hospital System 2013-05-31
NCT01583413 CDC Prevention Epicenters Wake Up and Breathe Collaborative https://ClinicalTrials.gov/show/NCT01583413 Completed Harvard Pilgrim Health Care 2013-06-30
NCT01559753 Early-onset Ventilator-associated Pneumonia in Adults: Comparison of 8 Versus 15 Days of Antibiotic Treatment https://ClinicalTrials.gov/show/NCT01559753 Completed Centre Hospitalier Universitaire de Besancon 2002-09-30
NCT01489124 The Population Pharmacokinetics of Imipenem in Patients With Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT01489124 Completed Prince of Songkla University 2009-01-31
NCT01477099 Toothbrushing and Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT01477099 Completed Hospital Universitario de Canarias 2011-08-31
NCT01467648 The Pharmacodynamics of Doripenem Between 4-hour and 1-hour Infusion in Patients With Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT01467648 Completed Prince of Songkla University 2011-10-31
NCT01382446 Chlorhexidine Gluconate Oral Care for Adults Experiencing Trauma https://ClinicalTrials.gov/show/NCT01382446 Completed St. Joseph’s Hospital and Medical Center, Phoenix 2012-04-30
NCT01379157 Pharmacodynamics Study of Imipenem in Patients With Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT01379157 Completed Prince of Songkla University 2013-08-31
NCT04346589 Convalescent Antibodies Infusion in Critically Ill COVID 19 Patients https://ClinicalTrials.gov/show/NCT04346589 Recruiting A.O. Ospedale Papa Giovanni XXIII 2020-08-31
NCT04323150 The Effect of Closed Suction System on the Incidence of Ventilator-associated Pneumonia. https://ClinicalTrials.gov/show/NCT04323150 Recruiting Northern State Medical University 2020-12-31
NCT04264533 Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia https://ClinicalTrials.gov/show/NCT04264533 Recruiting Zhongnan Hospital 2020-09-30
NCT04242706 VITAL - VAP Prevention by BIP (Bactiguard Infection Protection) ETT Evac in Belgian ICUs https://ClinicalTrials.gov/show/NCT04242706 Recruiting Bactiguard AB 2020-09-01
NCT04215692 Lung Ultrasound-guided Fluid Therapy in Pediatric Intensive Care Unit Patients https://ClinicalTrials.gov/show/NCT04215692 Recruiting Instituto Mexicano del Seguro Social 2020-06-01
NCT04208945 Nebulized Colistin for Gram Negative VAP Prevention. https://ClinicalTrials.gov/show/NCT04208945 Recruiting University of Thessaly 2021-04-30
NCT04061083 Effects of Endotracheal Tube Cuff Pressure Control on Microaspiration of Gastric Contents https://ClinicalTrials.gov/show/NCT04061083 Recruiting Afyonkarahisar University of Health Sciences 2019-12-01
NCT03921645 Use of Aaerosol Combined With Intravenous Antibiotics for the Treatment of Multidrug Resistant GNB Pneumonia https://ClinicalTrials.gov/show/NCT03921645 Recruiting Shanghai 10th People’s Hospital 2019-12-30
NCT03917888 Clinical Impact of Lung Ultrasound Monitoring for Diagnosis of VAP https://ClinicalTrials.gov/show/NCT03917888 Completed Tribhuvan University Teaching Hospital, Institute Of Medicine. 2018-08-10
NCT03816956 Adjunctive Therapy to Antibiotics in the Treatment of S. Aureus Ventilator-Associated Pneumonia With AR-301 https://ClinicalTrials.gov/show/NCT03816956 Recruiting Aridis Pharmaceuticals, Inc. 2020-08-31
NCT03749226 Nebulized Aztreonam for Prevention of Gram Negative Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT03749226 Recruiting Hospital Universitari Joan XXIII de Tarragona. 2019-09-04
NCT03705286 Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia https://ClinicalTrials.gov/show/NCT03705286 Active, not recruiting Oregon Health and Science University 2022-06-30
NCT03631342 Comparison Between Different Ventilator Hyperinflation Maneuvers https://ClinicalTrials.gov/show/NCT03631342 Completed Brazilian Institute of Higher Education of Censa 2017-09-30
NCT03622450 The Effect of Colistin Inhalation on Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT03622450 Completed Ain Shams University 2018-01-06
NCT03581370 Short Infusion Versus Prolonged Infusion of Ceftolozane-tazobactam Among Patients With Ventilator Associated-pneumonia https://ClinicalTrials.gov/show/NCT03581370 Recruiting University Hospital, Toulouse 2021-07-31
NCT03527992 Automated Oxygen Administration in Patients With Hypoxemic Pneumonia and Pleuropneumonia https://ClinicalTrials.gov/show/NCT03527992 Recruiting University Hospital, Toulouse 2021-09-30
NCT03506113 GRam Stain-guided Antibiotics ChoicE for Ventilator-Associated Pneumonia (GRACE-VAP) Trial https://ClinicalTrials.gov/show/NCT03506113 Active, not recruiting Osaka General Medical Center 2021-03-31
NCT03496220 Effect of Angulus on Patient-elevation Compliance https://ClinicalTrials.gov/show/NCT03496220 Recruiting Angulus, LLC 2018-12-30
NCT03477292 7-days Versus 14 Days of Antibiotics Therapy for Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT03477292 Recruiting Postgraduate Institute of Medical Education and Research 2020-04-15
NCT03442023 Different Oral Colonization of Gram-negative Bacteria in ICU Patients When Using Chlorhexidine at 0.12% Versus Chlorhexidine at 2.0% https://ClinicalTrials.gov/show/NCT03442023 Recruiting Universidad de Guanajuato 2019-11-30
NCT01770015 Bronchial Colonization With Fungi and Late Respiratory Acquired Pneumonia https://ClinicalTrials.gov/show/NCT01770015 Completed University Hospital, Grenoble 2016-03-31
NCT01188122 Optimal Endotracheal Cuff Pressure During Hospitalization in Intensive Care Units Using AnapnoGuard 100 System https://ClinicalTrials.gov/show/NCT01188122 Completed Hospitech Respiration 2009-09-30
NCT01150864 Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial https://ClinicalTrials.gov/show/NCT01150864 Completed Università degli Studi dell’Insubria 2015-03-31
NCT01126320 Frequency of Ventilator Associated Pneumonia (VAP) in Mechanically Ventilated Patients Using the AnapnoGuard System https://ClinicalTrials.gov/show/NCT01126320 Completed Hospitech Respiration 2015-07-31
NCT01105819 Chlorhexidine vs Lactobacillus Plantarum for Oral Care in Intubated ICU Patients https://ClinicalTrials.gov/show/NCT01105819 Completed Region Skane 2016-01-31
NCT01083407 Oral Care Interventions and Ventilator Associated Pneumonia in Critically Ill Children https://ClinicalTrials.gov/show/NCT01083407 Completed Federal University of São Paulo 2006-06-30
NCT01069185 Differences in Morbidity Between a Necessity Endotracheal Suctioning Protocol Versus a Routine Endotracheal Suctioning https://ClinicalTrials.gov/show/NCT01069185 Completed Hospital Pablo Tobón Uribe 2010-08-31
NCT01042353 Direct E-test on Bronchoalveolar Lavage From Patients With Ventilator-acquired Pneumonia https://ClinicalTrials.gov/show/NCT01042353 Completed Université Victor Segalen Bordeaux 2 NA
NCT00986102 PROUD Study: A Prospective Study on the Usage Patterns of Doripenem in the Asia Pacific Region https://ClinicalTrials.gov/show/NCT00986102 Completed Johnson & Johnson Pte Ltd 2011-09-30
NCT00975923 Safe Critical Care: Testing Improvement Strategies https://ClinicalTrials.gov/show/NCT00975923 Completed Vanderbilt University 2008-04-30
NCT00965848 A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections https://ClinicalTrials.gov/show/NCT00965848 Completed Janssen-Cilag Ltd.,Thailand 2010-07-31
NCT00950222 Impact of Imipenem With Amikacin Pharmacokinetic and Pharmacodynamic https://ClinicalTrials.gov/show/NCT00950222 Completed Assistance Publique - Hôpitaux de Paris 2011-09-30
NCT00893763 Strategies To Prevent Pneumonia 2 (SToPP2) https://ClinicalTrials.gov/show/NCT00893763 Completed University of South Florida 2012-06-30
NCT00876252 Study Assessing Immunogenicity and Safety of IC43 In Intensive Care Patients https://ClinicalTrials.gov/show/NCT00876252 Completed Valneva Austria GmbH 2010-02-28
NCT00851435 Safety and Pharmacokinetics of KBPA-101 in Hospital Acquired Pneumonia Caused by O11 Pseudomonas Aeruginosa https://ClinicalTrials.gov/show/NCT00851435 Completed Kenta Biotech Ltd 2009-07-31
NCT00829842 Oral Hygiene With Chlorhexidine and Incidence of Ventilator-Associated Pneumonia in Children Submitted to Heart Surgery https://ClinicalTrials.gov/show/NCT00829842 Completed University of Sao Paulo NA
NCT01577862 Colistin and Rifampicin for MDR-Acinetobacter https://ClinicalTrials.gov/show/NCT01577862 Completed University of Campania “Luigi Vanvitelli” 2011-08-31
NCT03711331 Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Patients With Hospital-acquired Pneumonia https://ClinicalTrials.gov/show/NCT03711331 Recruiting University Hospital, Lille 2021-01-31
NCT04325685 The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT04325685 Active, not recruiting Northern State Medical University 2021-12-31
NCT00786305 Nebulized Ceftazidime and Amikacin in Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT00786305 Completed Groupe Hospitalier Pitie-Salpetriere 2008-09-30
NCT00702871 A Clinico-Bacteriological Study and Effect of Stress Ulcer Prophylaxis on Occurrence of Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT00702871 Completed Maulana Azad Medical College 2006-04-30
NCT00702130 Pravastatin and Ventilatory Associated Pneumonia https://ClinicalTrials.gov/show/NCT00702130 Completed University of Thessaly 2010-04-30
NCT00691587 Pilot Trial of KB001 in Mechanically-Ventilated Patients Colonized With Pseudomonas Aeruginosa https://ClinicalTrials.gov/show/NCT00691587 Completed Humanigen, Inc. 2009-03-31
NCT00613795 Lactobacillus GG in the Prophylaxis of Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT00613795 Completed Creighton University 2009-08-31
NCT00610324 Effect of Oral Decontamination Using Chlorhexidine or Potassium Permanganate in ICU Patients https://ClinicalTrials.gov/show/NCT00610324 Completed King Edward Memorial Hospital 2007-10-31
NCT00604916 Oral Care Protocol for Preventing Ventilator- Associated Pneumonia https://ClinicalTrials.gov/show/NCT00604916 Completed Mackay Memorial Hospital 2007-11-30
NCT00597688 Role of Oral Chlorhexidine Gel in Prevention of Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT00597688 Completed All India Institute of Medical Sciences, New Delhi 2009-04-30
NCT00572559 Microbiologic Response With Linezolid And Vancomycin In Ventilator-Associated Pneumonia Due To Methicillin Resistant Staphylococcus Aureus https://ClinicalTrials.gov/show/NCT00572559 Completed Pfizer NA
NCT00542321 Pilot Study of Lateral Rotation Interventions for Efficacy and Safety in ICU Care https://ClinicalTrials.gov/show/NCT00542321 Completed The University of Texas Health Science Center, Houston 2011-09-30
NCT00529776 Prophylaxis of Ventilator Associated Pneumonia by Continuous Lateral Rotation Therapy https://ClinicalTrials.gov/show/NCT00529776 Completed Medical University of Vienna NA
NCT00521677 Comparison Between Two Methods of Oral Care on the Incidence of VAP https://ClinicalTrials.gov/show/NCT00521677 Completed HaEmek Medical Center, Israel 2009-02-28
NCT00518752 Effects of Oral Care in the Neuroscience ICU https://ClinicalTrials.gov/show/NCT00518752 Completed St. Joseph’s Hospital and Medical Center, Phoenix 2011-03-31
NCT00515034 A Safety and Tolerability Study of Doripenem in Patients With Abdominal Infections or Pneumonia https://ClinicalTrials.gov/show/NCT00515034 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 2008-11-30
NCT00502801 An Effectiveness, Safety, and Microbiology Study of Doripenem in Patients With Nosocomial (Hospital-acquired) Pneumonia https://ClinicalTrials.gov/show/NCT00502801 Completed PriCara, Unit of Ortho-McNeil, Inc. 2008-11-30
NCT00495963 Diagnosis of Ventilator- Associated Pneumonia in Children: A Comparative Study of Bronchoscopic and Non-Bronchoscopic Methods https://ClinicalTrials.gov/show/NCT00495963 Completed Sir Ganga Ram Hospital NA
NCT00491660 Effect of Gravity on Tracheal Colonization During Mechanical Ventilation in Infants https://ClinicalTrials.gov/show/NCT00491660 Completed Cairo University NA
NCT00475579 Endotracheal Tube With Polyurethane Cuff and Subglottic Secretion Drainage https://ClinicalTrials.gov/show/NCT00475579 Completed Hospital Universitario de Canarias NA
NCT00447239 The Effect of Intensive Insulin Therapy https://ClinicalTrials.gov/show/NCT00447239 Completed University Medical Centre Ljubljana NA
NCT00447109 Time Interval for Changing Closed System Suction Catheters, Effect on Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT00447109 Completed Bayside Health NA
NCT00432718 Saline Instillation Before Tracheal Suctioning and the Incidence of Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT00432718 Completed Hospital do Cancer, Sao Paulo NA
NCT00396578 Aerosolized Antibiotics and Respiratory Tract Infection in Patients on Mechanical Ventilation https://ClinicalTrials.gov/show/NCT00396578 Completed Stony Brook University NA
NCT00364299 Prevention of Ventilator-Associated Pneumonia by Automatic Control of the Tracheal Tube Cuff Pressure https://ClinicalTrials.gov/show/NCT00364299 Completed Hospital Clinic of Barcelona NA
NCT00332982 Ontario ICU Clinical Best Practices Demonstration Project https://ClinicalTrials.gov/show/NCT00332982 Completed Sunnybrook Health Sciences Centre NA
NCT00319644 Impact of Using Mini-Bronchoalveolar Lavage as a Diagnostic Test for Ventilator-Associated Pneumonia https://ClinicalTrials.gov/show/NCT00319644 Completed University of California, San Francisco 2008-12-31
NCT00297674 Intravenous Clarithromycin in Septic Syndrome https://ClinicalTrials.gov/show/NCT00297674 Completed University of Athens NA
NCT00234598 Strategies to Prevent Pneumonia (SToP Pneumonia) https://ClinicalTrials.gov/show/NCT00234598 Completed Virginia Commonwealth University 2008-02-29
NCT00211016 Doripenem in the Treatment of Ventilator-Associated Pneumonia https://ClinicalTrials.gov/show/NCT00211016 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. NA
NCT00148642 Silver-Coated Endotracheal Tube to Reduce Ventilator Associated Pneumonia (VAP) https://ClinicalTrials.gov/show/NCT00148642 Completed C. R. Bard 2006-03-31
NCT00050401 Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support https://ClinicalTrials.gov/show/NCT00050401 Completed Pfizer 2004-09-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03303937 Characteristics of Lower Respiratory Tract Escherichia Coli Isolates in Mechanically Ventilated Intensive Care Patients https://ClinicalTrials.gov/show/NCT03303937 Completed Hôpital Louis Mourier 2015-06-10
NCT03290105 Microbial and Pharmacological Assessment of Chlorhexidine https://ClinicalTrials.gov/show/NCT03290105 Completed Hôpital Louis Mourier 2014-03-31
NCT03053258 Diagnostic Breath Analysis for Detection of Ventilator Acquired Pneumonia (VAP) https://ClinicalTrials.gov/show/NCT03053258 Completed Landon Pediatric Foundation 2018-10-31
NCT03041207 Decreasing Antibiotic Use in Infants With Suspected Ventilator-associated Infection https://ClinicalTrials.gov/show/NCT03041207 Completed Virginia Commonwealth University 2019-04-30
NCT02779933 Epidemiology of Risk Factors for Hospital-acquired Pneumonia (HAP) in Intensive Care Unit (ICU) Patients https://ClinicalTrials.gov/show/NCT02779933 Completed University Hospital Olomouc 2015-12-31
NCT02689531 CTTI Risk Factors for HABP/VABP Study https://ClinicalTrials.gov/show/NCT02689531 Completed Duke University 2018-02-28
NCT02683122 The DIPOD Study (Diagnosis Improvement of Pneumonia by Organ Dysfunction) https://ClinicalTrials.gov/show/NCT02683122 Completed Centre Chirurgical Marie Lannelongue 2016-12-31
NCT02536547 Diagnostic Value of Pulmonary Ultrasound in the Diagnosis of Ventilator-associated Pneumoniae https://ClinicalTrials.gov/show/NCT02536547 Completed Groupe Hospitalier Paris Saint Joseph 2014-06-30
NCT02413242 Advanced Understanding of Staphylococcus Aureus and Pseudomonas Aeruginosa Infections in EuRopE - ICU https://ClinicalTrials.gov/show/NCT02413242 Completed UMC Utrecht 2019-04-30
NCT02400294 Prevention of Ventilator Associated Pneumonia With Toothbrushing in Oral Care of Critically Ill Mechanically Ventilated Patients https://ClinicalTrials.gov/show/NCT02400294 Completed University Hospital, Clermont-Ferrand 2015-07-31
NCT02244723 Diagnostic Value of Lung Ultrasound for Ventilator-Associated Pneumonia https://ClinicalTrials.gov/show/NCT02244723 Completed Groupe Hospitalier Paris Saint Joseph 2015-01-01
NCT02078999 Biomarkers in Patients Undergoing Mechanical Ventilation https://ClinicalTrials.gov/show/NCT02078999 Completed Corporacion Parc Tauli 2010-09-30
NCT01294943 Evaluating the Effectiveness of the Tongue Cleaner in Critical Patients https://ClinicalTrials.gov/show/NCT01294943 Completed University of Sao Paulo 2011-06-30
NCT02019095 Clinical and Biological Markers in Acute Respiratory Failure https://ClinicalTrials.gov/show/NCT02019095 Completed University of Athens 2014-12-31
NCT01902446 Prehospital Ventilator-Associated Pneumonia Prevention Trial https://ClinicalTrials.gov/show/NCT01902446 Completed University of Iowa 2014-10-31
NCT01894347 Prospective Observational Pilot-study for the Evaluation of the Nephro- an Neurotoxicity in the Anti-infectious Therapy With Inhalative Colistin Therapy for Patients With Ventilator-associated Pneumonia (VAP) https://ClinicalTrials.gov/show/NCT01894347 Completed Charite University, Berlin, Germany 2015-04-30
NCT01875692 Can we Better Understand the Development of VAP and Eventually Predict and Prevent it? https://ClinicalTrials.gov/show/NCT01875692 Completed University Hospital, Geneva 2014-03-31
NCT01406951 Diagnostic Value of sTREM-1 and PCT Level as Well as CPIS Score for Ventilator-Associated Pneumonia Among ICU Sepsis Patients https://ClinicalTrials.gov/show/NCT01406951 Completed Chinese PLA General Hospital 2011-03-31
NCT04372576 Epidemiology and Outcome of Ventilator-associated Pneumonia Among Critically Ill COVID-19 Patients https://ClinicalTrials.gov/show/NCT04372576 Recruiting Semmelweis University 2020-08-31
NCT04352855 Ceftolozane-tazobactam for the Treatment of Respiratory Infections Due to Extensively Drug-resistant Pseudomonas Aeruginosa Among Critically Ill Patients: a Retrospective Study. https://ClinicalTrials.gov/show/NCT04352855 Active, not recruiting Semmelweis University 2020-05-19
NCT04313946 Artificial Intelligence Algorithms for Discriminating Between COVID-19 and Influenza Pneumonitis Using Chest X-Rays https://ClinicalTrials.gov/show/NCT04313946 Recruiting Grigore T. Popa University of Medicine and Pharmacy 2020-08-16
NCT04233268 RASCALS: Rapid Assay for Sick Children With Acute Lung Infection Study https://ClinicalTrials.gov/show/NCT04233268 Recruiting Cambridge University Hospitals NHS Foundation Trust 2023-02-28
NCT04097899 Antimicrobial Stewardship Program and Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT04097899 Completed Zagazig University 2017-12-31
NCT04038814 The Effectiveness of the Modified Bundle in the Prevention of VAP. https://ClinicalTrials.gov/show/NCT04038814 Completed Andrzej Frycz Modrzewski Krakow University 2019-07-01
NCT03937947 Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study https://ClinicalTrials.gov/show/NCT03937947 Recruiting NHS Lothian 2020-10-31
NCT03763695 Effectiveness of a VAP Prevention Bundle in the PICU https://ClinicalTrials.gov/show/NCT03763695 Recruiting Fondazione Policlinico Universitario Agostino Gemelli IRCCS 2019-12-31
NCT03506191 Pneumonia Due to Stenotrophomonas Maltophilia in ICUs https://ClinicalTrials.gov/show/NCT03506191 Active, not recruiting Groupe Hospitalier Pitie-Salpetriere 2018-07-30
NCT01135277 Immune Suppression and Ventilator Associated Pneumonias https://ClinicalTrials.gov/show/NCT01135277 Completed Ohio State University 2012-11-30
NCT01110109 Removing Fluid Above Breathing Tubes in the Operating Room https://ClinicalTrials.gov/show/NCT01110109 Completed Medtronic - MITG 2010-09-30
NCT00976157 Serial Changes in sTREM-1 During Ventilator-associated Pneumonia (VAP) https://ClinicalTrials.gov/show/NCT00976157 Completed Mackay Memorial Hospital 2007-12-31
NCT00938002 Study to Determine Quicker Methods of Diagnosing Pneumonia Caused by a Breathing Machine in Critically Ill Patients https://ClinicalTrials.gov/show/NCT00938002 Completed Denver Health and Hospital Authority 2019-09-19
NCT03434821 Hyperoxemia and Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT03434821 Recruiting University Hospital, Lille 2021-04-30
NCT00726167 Serum Procalcitonin Study in the Management of Ventilated Patients https://ClinicalTrials.gov/show/NCT00726167 Completed University of Missouri-Columbia 2014-08-31
NCT00484588 A Multi-Center Observational Surveillance Study of VAP Causing Bacteria https://ClinicalTrials.gov/show/NCT00484588 Completed Wyeth is now a wholly owned subsidiary of Pfizer NA
NCT00434460 Study of Knowledge Translation of Clinical Practice Guidelines for Ventilator Associated Pneumonia https://ClinicalTrials.gov/show/NCT00434460 Completed Canadian Critical Care Trials Group NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02928042 Inhibition Effects of Probiotics on Pathogens Associated With VAP https://ClinicalTrials.gov/show/NCT02928042 Completed Cukurova University 2018-01-31
NCT03348579 Hospital-acquired Pneumonia in Intensive Care Unit https://ClinicalTrials.gov/show/NCT03348579 Completed Nantes University Hospital 2018-10-15
NCT04402359 Usage of Meropenem/Gentamicin Versus Ceftazidime/Avibactam in ARDS https://ClinicalTrials.gov/show/NCT04402359 Completed King Abdul Aziz Specialist Hospital 2019-12-28
NCT04397952 Endotracheal Tube Cuff Pressure Measurement https://ClinicalTrials.gov/show/NCT04397952 Completed Bagcilar Training and Research Hospital 2018-04-15
NCT04348227 How COVID-19 Virus Outbreak Affects Antimicrobial Resistance in a Low-middle-income Country’s ICU? https://ClinicalTrials.gov/show/NCT04348227 Active, not recruiting Hôpital Universitaire Fattouma Bourguiba 2020-01-01
NCT04149665 Semirecumbent Position by Mechanical Ventilation https://ClinicalTrials.gov/show/NCT04149665 Recruiting Bürgerspital Solothurn 2020-01-15